Neurodegenerative processes of dementia could play a key role in the pathogenesis of epilepsy in a subgroup of individuals intended to develop cognitive decline. The hypothesis is that adult-onset epilepsy of undefined cause could represent a risk factor for the ongoing neurodegenerative damage, even preceding by years the onset of clinical symptoms of dementia.

J Alzheimers Dis. 2017 Sep 28. doi: 10.3233/JAD-170392. [Epub ahead of print]